Publications

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Strack, D., Dieckmeyer, M., Sollmann, N., Baum, T., Kirschke, J. S. & Subburaj, K. (2026). Vertebral-level discrimination of incidental vertebral fractures using volumetric BMD, texture features, and finite element–derived fracture load: an exploratory study. Skeletal Radiology. Advance online publication. https://doi.org/10.1007/s00256-026-05147-w

Hesse, N., Strack, D., Rischewski, J. F., Gassert, F. T., Kufner, A., Urban, T., Lochschmidt, M. E., Schwaiger, B. J., Braun, C., Mueller, D. P., Pfeiffer, D., Baum, T., Subburaj, K., Pfeiffer, F. & Gersing, A. S. (2025). Finite element fracture load analysis and dark-field X-ray imaging of osteoporotic and healthy vertebrae in human lumbar spine specimens. BMC Musculoskeletal Disorders, 26(1), Article 545. https://doi.org/10.1186/s12891-025-08709-6

Karupppasamy, S. (2025). Pragmatic customization in medical device design for sustainable healthcare. In P. Kyratsis, A. Manavis & P. J. Davim (Eds.), CAD/CAM: Computer-Aided Design and Manufacturing, (pp. 143). De Gruyter. https://doi.org/10.1515/9783111585062-007

Kaur, S., Sandhu, K., Sarkar, P. & Subburaj, K. (2025). Understanding User Experience: Exploration of Various Definitions Using Natural Language Process. In A. Chakrabarti, V. Singh, P. S. Onkar & M. Shahid (Eds.), Responsible and Resilient Design for Society: Proceedings of ICoRD 2025 (Vol. 4, pp. 231-241). Springer. https://doi.org/10.1007/978-981-96-5495-6_18

Lerchl, T., Strack, D., Allaire, B., Yee, E., Scott, R., Nispel, K., Moeller, H., Graf, R., Karupppasamy, S., Kirschke , J. S., Bouxsein, M. L. & Anderson, D. E. (2025). THE EFFECTS OF PREVALENT VERTEBRAL FRACTURES ON SPINAL BIOMECHANICS. Abstract from 20th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Barcelona, Spain. https://www.researchgate.net/publication/397941200_THE_EFFECTS_OF_PREVALENT_VERTEBRAL_FRACTURES_ON_SPINAL_BIOMECHANICS

Sandhu, K., Karupppasamy, S., Pal, M., Sarkar, P. & Singh, S. (Eds.) (2025). Footwear Innovation: From Conceptual Design through to Advanced Manufacturing Techniques. (1 ed.) Elsevier, Academic Press. https://doi.org/10.1016/C2023-0-52605-9

Sandhu, K., Sarkar, P. & Karupppasamy, S. (2025). Understanding entrepreneurial thinking for designers: Perspectives from entrepreneurs, academicians, product designers, and students. Thinking Skills and Creativity, 56, Article 101728. https://doi.org/10.1016/j.tsc.2024.101728

Sandhu, K., Sarkar, P. & Subburaj, K. (2025). Entrepreneurial thinking in engineering design education: a comparative study of cognitive paradigms with insights from industry and academia. Entrepreneurship Education. Advance online publication. https://doi.org/10.1007/s41959-025-00158-5

Sandhu, K., Sarkar, P. & Subburaj, K. (2025). Identification of Skills for Entrepreneurial Thinking Using Natural Language Processing: An Exploration of Entrepreneurs, Faculties Members and Design Students. In A. Chakrabarti, V. Singh, P. S. Onkar & M. Shahid (Eds.), Responsible and Resilient Design for Society - Proceedings of ICoRD 2025 (Vol. 4, pp. 255-266). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-981-96-5495-6_20

Sandhu, K., Singh, G., Subburaj, K., Sarkar, P. & Pal, M. (2025). Introduction. In Footwear Innovation: From Conceptual Design through to Advanced Manufacturing Techniques (pp. 3-6). Elsevier. https://doi.org/10.1016/B978-0-443-26751-2.00025-3

Strack, D., Mesbah, M., Kirschke , J. S. & Karupppasamy, S. (2025). Biomechanical Alterations Following Vertebral Fracture: A Patient-Specific L3-L5 Finite Element Analysis. Abstract from World Congress of Orthopaedic Research, Adelaide, South Australia, Australia. https://doi.org/10.13140/RG.2.2.28212.10884

Strack, D., Mesbah, M., Kirschke , J. S., Baum, T. & Karupppasamy, S. (2025). Interpatient variability and validation of simplified L4-L5 Finite Element Model. Abstract from The XXX Congress of the International Society of Biomechanics , Stockholm, Sweden. https://www.researchgate.net/publication/395188992_Interpatient_variability_and_validation_of_simplified_L4-L5_Finite_Element_Model

Strack, D., Dieckmeyer, M., Sollmann , N., Kirschke , J. S. & Karupppasamy, S. (2025). Unexpectedly Higher Finite Element-Derived Strength in Fractured Vertebrae: Insights from a Retrospective Study. Abstract from Annual Meeting of the American Society of Bone and Mineral Research, Seattle, Washington, United States. https://doi.org/10.13140/RG.2.2.18868.72321

Vishnu, K., Subburaj, K. & Colombo, M. (2025). A two-phase fluid structure interaction model of mucociliary clearance driven by cilium. Computer Methods in Biomechanics and Biomedical Engineering. Advance online publication. https://doi.org/10.1080/10255842.2025.2535014

Yee, A. Z. H., Kwok, B., Ng, J., Loy, G. P., Ng, L. Y., Sng, J. R. H., Perrault, S., Lim, K. H. & Subburaj, K. (2025). Why Older Adults Integrate Digital Health Technology Into Their Everyday Lives: The Role of Basic Psychological Needs. Human Behavior and Emerging Technologies, 2025(1), Article 9711661. https://doi.org/10.1155/hbe2/9711661

Karupppasamy, S., Singh, S., Ćuković, S., Sandhu, K., Meixner, G. & Petruse, R. E. (Eds.) (2024). Smart VR/AR/MR Systems for Professionals. CRC Press. https://doi.org/10.1201/9781003306078

Strack, D., Mesbah, M., Manohar Rayudu, N., Baum, T., Kirschke , J. S. & Karupppasamy, S. (2024). IMPACT OF ANNULUS FIBROSUS STIFFNESS ON THE FRACTURE LOAD OF FUNCTIONAL SPINE UNITS. Orthopaedic Proceedings, 102. https://doi.org/10.1302/1358-992X.2024.18.102

Strack, D., Manohar Rayudu, N., Kirschke , J. S., Baum, T. & Karupppasamy, S. (2024). OPTIMIZING PATIENT-SPECIFIC BONE FINITE ELEMENT ANALYSIS: MESH CONVERGENCE AND MATERIAL GROUPING STRATEGIES. Orthopaedic Proceedings, 127. https://doi.org/10.1302/1358-992X.2024.18.127

Velu, R., Karupppasamy, S. & Kumar Subramaniyan, A. K. (Eds.) (2024). Digital Design and Manufacturing of Medical Devices and Systems. (1 ed.) Springer. https://doi.org/10.1007/978-981-99-7100-8

Binedell, T., Gupta, U., Sithanathan, B., Karupppasamy, S. & Blessing, L. (2023). Mapping lines of non-extension in persons with lower limb amputation to aid comfort-driven prosthetic socket design. Medical Engineering & Physics, 118, Article 104018. https://doi.org/10.1016/j.medengphy.2023.104018

Binedell, T., Fazli Bin Ghazali, M., Wong, C., Karupppasamy, S. & Blessing, L. (2023). Measuring discomfort—An objective method for quantifying peak pressure discomfort and improved fit in adults with transtibial amputation. PM & R, 15(4), 482-492. https://doi.org/10.1002/pmrj.12796

Bodden, J., Dieckmeyer, M., Sollmann , N., Rühling, S., Prucker, P., T. Löffler, M., Burian, E., Karupppasamy, S., Zimmer, C., Kirschke , J. S. & Baum, T. (2023). Long-term reproducibility of opportunistically assessed vertebral bone mineral density and texture features in routine clinical multi-detector computed tomography using an automated segmentation framework. Quantitative Imaging in Medicine and Surgery (QIMS), 13(9), 5472-5482. https://doi.org/10.21037/qims-23-19

Kumar , R., Sandhu, K., Ranjan, N., Singh, S., Sarkar, P., Karupppasamy, S. & Ramakrishna, S. (2023). Form exploration on different fabrics using material extrusion based additive manufacturing and end users experience. Journal of Manufacturing Processes, 101, 959-973. https://doi.org/10.1016/j.jmapro.2023.06.053

Srinivasan, V., Song, B., Luo, J., Karupppasamy, S., Elara Mohan, R., Blessing, L. & Wood, K. (2023). Do Analogies and Analogical Distance Influence Ideation Outcomes in Engineering Design? In S. Mukherjee, V. Dutt & N. Srinivasan (Eds.), Applied Cognitive Science and Technology: Implications of Interactions Between Human Cognition and Technology (pp. 211–230). Springer. https://doi.org/10.1007/978-981-99-3966-4_13

Binedell, T. & Karupppasamy, S. (2022). Design for Additive Manufacturing of Prosthetic and Orthotic Devices. In S. Karupppasamy , S. Kamalpreet & S. Ćuković (Eds.), Revolutions in Product Design for Healthcare: Advances in Product Design and Design Methods for Healthcare (pp. 75–99). Springer. https://doi.org/10.1007/978-981-16-9455-4

Dieckmeyer, M., Sollmann , N., El Husseini, M., Sekuboyina, A., T. Löffler, M., Zimmer, C., Kirschke , J. S., Karupppasamy, S. & Baum, T. (2022). Gender-, Age- and Region-Specific Characterization of Vertebral Bone Microstructure Through Automated Segmentation and 3D Texture Analysis of Routine Abdominal CT. Frontiers in Endocrinology, 12, Article 792760. https://doi.org/10.3389/fendo.2021.792760

Go, Y., Etsuo, C., Duraisamy, S. & Karupppasamy, S. (2022). Meniscus implant. (Patent No. WO2022065312 (A1)). https://dk.espacenet.com/publicationDetails/biblio?CC=WO&NR=2022065312A1&KC=A1&FT=D&ND=3&date=20220331&DB=EPODOC&locale=dk_DK#

Greve, T., Manohar Rayudu, N., Dieckmeyer, M., Boehm, C., Ruschke, S., Burian, E., Kloth, C., Kirschke , J. S., Charalampos Karampinos, D., Baum, T., Karupppasamy, S. & Sollmann , N. (2022). Finite element analysis of osteoporotic and osteoblastic vertebrae and its association with the proton density fat fraction from chemical shift encoding-based water-fat MRI – a preliminary study. Frontiers in Endocrinology, 13, Article 900356. https://doi.org/10.3389/fendo.2022.900356

Kamalpreet , S., Singh, S., Prakash, C., Karupppasamy, S. & Ramakrishnaa , S. (Eds.) (2022). 3D Printing in Podiatric Medicine. Academic Press. https://www.elsevier.com/books/3d-printing-in-podiatric-medicine/sandhu/978-0-323-91911-1

Karupppasamy, S., Kamalpreet , S. & Saša Ćuković, S. Ć. (Eds.) (2022). Revolutions in Product Design for Healthcare: Advances in Product Design and Design Methods for Healthcare. Springer. Design Science and Innovation https://doi.org/10.1007/978-981-16-9455-4

Leonhardt, Y., Dieckmeyer, M., Zoffl , F., Feuerriegel, G. C., Sollmann , N., Junker, D., Greve, T., Holzapfel , C., Hauner, H., Karupppasamy, S., Kirschke , J. S., Karampinos, D. C., Zimmer, C., Makowski , M. R., Baum, T. & Burian, E. (2022). Associations of Texture Features of Proton Density Fat Fraction Maps between Lumbar Vertebral Bone Marrow and Paraspinal Musculature. Biomedicines, 10(9), Article 2075. https://doi.org/10.3390/biomedicines10092075

Long Yu, Y. & Karupppasamy, S. (2022). 3D-Printed Orthotics for Pediatric Lower Limb Deformities Correction. In 3D Printing in Pediatric Medicine (pp. 51-82). Academic Press. https://www.sciencedirect.com/science/article/pii/B9780323919111000031?via%3Dihub

Manohar Rayudu, N., Karupppasamy, S., Elara Mohan, R., Sollmann , N., Dieckmeyer, M., Kirschke , J. S. & Baum, T. (2022). Patient-Specific Finite Element Modeling of the Whole Lumbar Spine Using Clinical Routine Multi-Detector Computed Tomography (MDCT) Data—A Pilot Study. Biomedicines, 10(7), Article 1567. https://doi.org/10.3390/biomedicines10071567

Nagarajan, K., Koronis, G., Karupppasamy, S. & Silva, A. (2022). Atypical Use Scenarios as Design Intervention in Healthcare Product Design Application. In Proceedings of the Design Society 2: DESIGN2022 (Vol. 2, pp. 1323-1330). Cambridge University Press. https://doi.org/10.1017/pds.2022.134

Rai, P., Jankiraman, V., Teacher, M., Velu, R., Anand Kumar, S., Binedell, T. & Karupppasamy, S. (2022). Design and optimization of a 3D printed prosthetic socket for transtibial amputees, Materials Today: Proceedings, 70, 454-464. https://doi.org/10.1016/j.matpr.2022.09.365

Raviselvam, S., Karupppasamy, S., Hölttä-Otto, K. & L. Wood, K. (2022). Systematic Application of Extreme-User Experiences: Impact on the Outcomes of an Undergraduate Medical Device Design Module. Biomedical Engineering Education, 2, 233–252. https://doi.org/10.1007/s43683-022-00065-4

Sollmann , N., Kirscke, J. S., Kronthaler, S., Boehm, C., Dieckmeyer, M., Vogele, D., Kloth, C., Lisson, C. G., Carballido-Gamio, J., Link, T. M., Charalampos Karampinos, D., Karupppasamy, S., Beer, M., Krug, R. & Baum, T. (2022). Imaging of the Osteoporotic Spine – Quantitative Approaches in Diagnostics and for the Prediction of the Individual Fracture Risk: Bildgebung der osteoporotischen Wirbelsäule – quantitative Ansätze für die Diagnostik und Abschätzung des individuellen Frakturrisikos. RöFo. Fortschritte auf dem Gebiet der Roentgenstrahlen und der bildgebenden Verfahren, 194(10), 1088-1099. https://doi.org/10.1055/a-1770-4626

Sollmann , N., A. Becherucci, E., Boehm, C., El Husseini, M., Ruschke, S., Burian, E., Kirschke , J. S., Link, T. M., Karupppasamy, S., Charalampos Karampinos, D., Krug, R., Baum, T. & Dieckmeyer, M. (2022). Texture Analysis using CT and Chemical Shift Encoding-Based Water-Fat MRI can Improve Differentiation between Patients with and without Osteoporotic Vertebral Fractures. Frontiers in Endocrinology, 12, Article 778537. https://doi.org/10.3389/fendo.2021.778537

Kalimeri, M., Totman, J. J., Baum, T., Diefenbach, M. N., Hauner, H., Makowski, M. R., Subburaj, K., Cameron-Smith, D., Henry, C. J., Karampinos, D. C. & Junker, D. (2021). Postmenopausal chinese-singaporean women have a higher ratio of visceral to subcutaneous adipose tissue volume than caucasian women of the same age and bmi. Diagnostics, 11(11), Article 2127. https://doi.org/10.3390/diagnostics11112127

Chandran, R., Lim, J. K. T., Koo, S. H., Karupppasamy, S., Lim, J. H., Poh, Y. J. V., Ong, P. J. J. & Lu, W. Y. (2020). A Guidewire Management Device. (Patent No. WO2020256642 (A1)). https://dk.espacenet.com/publicationDetails/biblio?CC=WO&NR=2020256642A1&KC=A1&FT=D&ND=3&date=20201224&DB=EPODOC&locale=dk_DK#

Loh, C. Y. I., Tay, Y. E., Karupppasamy, S., Phang, T. A., Sim, M. Y., Ng, B. & Sin, V. (2020). Device for Skin Biopsy. (Patent No. WO2020167250 (A1)). https://dk.espacenet.com/publicationDetails/biblio?CC=WO&NR=2020167250A1&KC=A1&FT=D&ND=3&date=20200820&DB=EPODOC&locale=dk_DK#

Ng, F. C., Lim, S. K. T., Karupppasamy, S., Tan, U.-X., Chen, L., Foong, S., Yang, L., Li, H.-Y., Paranawithana, I. C. K., Chau, Z. H. & Mookiah, M. R. K. (2019). Motion Compensation Platform for Image Guided Percutaneous Access to Bodily Organs and Structures. (Patent No. WO2019132781 (A1)). https://dk.espacenet.com/publicationDetails/biblio?CC=WO&NR=2019132781A1&KC=A1&FT=D&ND=3&date=20190704&DB=EPODOC&locale=dk_DK#

Mookiah, M. R. K., Rohrmeier, A., Dieckmeyer, M., Mei, K., K. Kopp, F., B. Noël, P., Kirschke , J. S., Baum, T. & Karupppasamy, S. (2018). Feasibility of opportunistic osteoporosis screening in routine contrast-enhanced Multi-Detector Computed Tomography using texture analysis. Osteoporosis International, 29(4), 825-835. https://doi.org/10.1007/s00198-017-4342-3

Cukovic, S., Devedzic, G., Ivanovic, L., Lukovic, T. Z. & Subburaj, K. (2010). Development of 3D kinematic model of the spine for idiopathic scoliosis simulation. Computer-Aided Design and Applications, 7(1), 153-161. https://doi.org/10.3722/cadaps.2010.153-161

Subburaj, K., Ravi, B. & Agarwal, M. G. (2009). Computerized Assessment of Excessive Femoral and Tibial Torsional Deformation by 3D Anatomical Landmarks Referencing. In 13th International Conference on Biomedical Engineering - ICBME 2008 (pp. 129-132) https://doi.org/10.1007/978-3-540-92841-6_32

Pal, D. K., Raychaudhuri, T. K., Ravi, B. & Subburaj, K. (2007). Rapid Tooling route selection and evaluation for sand and investment casting. In Proceedings of the 3rd International Conference on Advanced Research in Virtual and Rapid Prototyping: Virtual and Rapid Manufacturing Advanced Research Virtual and Rapid Prototyping (pp. 455-462)

Revised 13.11.2025

Subburaj Karupppasamy