I am an Associate Professor at the Department of Biomedicine at Aarhus University, working at the interface of functional immunology, bioanalytics and technology development. My research focuses on understanding immune responses at the level of individual cells, with particular emphasis on functional heterogeneity, cellular dynamics and antibody responses.
My research focuses on understanding immune responses at the level of individual cells. Immune cells with similar molecular phenotypes can display profoundly different functional behaviours, including differences in secretion, metabolism, responsiveness and persistence. We therefore develop quantitative approaches to measure what individual cells actually do, and how their functional behaviour changes over time, and apply them in various translational applications with our clinical and fundamental collaboration partners.
At AU, I contribute to teaching across different levels. At the bachelor level, I have participated in teaching the pharmacology course (15 ECTS) for approximately 300 medical students each semester, delivering lectures with associated exercises and supporting examination, as well as the pharmacology and drug development course for molecular medicine students. I have also supervised bachelor students on theoretical and empirical projects, providing one-on-one mentoring and peer feedback. At the doctoral level, I serve as responsible coordinator for the Transcend network. Also, I am in charge of the PhD course for 'From Numbers to Knowledge: Measurement Theory in the Biomedical Sciences' (4.9 ECTS), a new course I have designed for our doctoral students.
My research is inherently interdisciplinary, combining immunology with bioanalytics, microfluidics, biotechnology, quantitative measurement and computational analysis. I collaborate with researchers across disciplines to develop new measurement technologies and apply them to important biomedical questions.
I am particularly interested in collaborations in which methodological development and biological discovery are closely connected, allowing advances in technology to open new scientific questions and biological challenges to drive the development of new analytical approaches or their application.
I provide research-based consultancy within single-cell analysis, functional immunology, bioanalytics and biotechnology. My consultancy activities are based on expertise in the development and application of quantitative single-cell technologies, microfluidics, immune profiling and functional assays.
I advise academic and industrial partners on experimental strategy, assay development, technology evaluation and the application of single-cell approaches to biomedical and translational research questions. My consultancy experience also includes supporting the development and translation of emerging technologies towards applications in biotechnology and life-science research.
My work focuses on quantitative analysis of immune function at the single-cell level, combining microfluidics, high-dimensional phenotyping and functional assays to understand immune-cell heterogeneity, dynamics and mechanisms of health, prevention and disease. My research spans fundamental immunology, infection, vaccination, autoimmunity and cancer, with a particular interest in translating functional immune profiling and antibody repertoire analysis into improved diagnostics, patient stratification and precision medicine. I specifically try to work at the interface of academic research, clinical collaboration and technological innovation.
